In the somatosensory laboratories at ISR, physiological, anatomical, neurochemical, behavioral, and computational approaches are used to understand basic science aspects of tactile, thermal and pain perceptions. Research is aimed at uncovering basic transduction mechanisms at the membrane level, and biological phenomenon that allow the brain to interpret stimuli in the environment. Parallel studies are conducted that utilize the basic concepts of somatosensation for the purposes of improved healthcare and consumer-product development. For example, research and development are being performed to provide aids for the visual and hearing impaired, for better sensory-motor coordination in the elderly and neurologically- challenged, and for therapeutic strategies to control chronic pain. Research and development also addresses issues such as defining "pleasurable" sensations and comfort as they relate to personal care products for the skin. It is the working philosophy of those associated with the laboratory that through basic research, the enhancement of somatosensory experiences can lead to improved living situations. The laboratory works with colleagues throughout the world, some located at academic institutions, others located in the industrial and manufacturing sectors, and the U.S. Armed Forces.

A microscopic view of a cluster of Pacinian corpuscles, cells that detect vibration of the skin.

Microscopic illumination of the lamellae (inner layers) of the Pacinian corpuscle (skin mechanoreceptor).